Auflistung nach Schlagwort "Protein Biosynthesis"

Sortiert nach: Sortierung: Ergebnisse:

  • Computational analysis of protein synthesis, diffusion, and binding in compartmental biochips 
    Förste, Stefanie; Vonshak, Ohad; Daube, Shirley S.; Bar-Ziv, Roy H.; Lipowsky, Reinhard; Rudorf, Sophia (London : Biomed Central, 2023)
    Protein complex assembly facilitates the combination of individual protein subunits into functional entities, and thus plays a crucial role in biology and biotechnology. Recently, we developed quasi-twodimensional, ...
  • Decomposing bulk signals to reveal hidden information in processive enzyme reactions: A case study in mRNA translation 
    Haase, Nadin; Holtkamp, Wolf; Christ, Simon; Heinemann, Dag; Rodnina, Marina V.; Rudorf, Sophia (San Francisco, Calif. : Public Library of Science, 2024)
    Processive enzymes like polymerases or ribosomes are often studied in bulk experiments by monitoring time-dependent signals, such as fluorescence time traces. However, due to biomolecular process stochasticity, ensemble ...
  • Dominance analysis of competing protein assembly pathways 
    Lankeit, Johannes; Förste, Stefanie; Rudorf, Sophia (San Francisco, California, US : PLOS, 2023)
    Most proteins form complexes consisting of two or more subunits, where complex assembly can proceed via two competing pathways: co-translational assembly of a mature and a nascent subunit, and post-translational assembly ...
  • Minimum Information about a Biosynthetic Gene cluster 
    Medema, Marnix H.; Kottmann, Renzo; Yilmaz, Pelin; Cummings, Matthew; Biggins, John B.; Cox, Russell J.; et al. (London : Nature Publishing Group, 2015)
    A wide variety of enzymatic pathways that produce specialized metabolites in bacteria, fungi and plants are known to be encoded in biosynthetic gene clusters. Information about these clusters, pathways and metabolites is ...
  • The Myxobacterial Antibiotic Myxovalargin: Biosynthesis, Structural Revision, Total Synthesis, and Molecular Characterization of Ribosomal Inhibition 
    Koller, Timm O.; Scheid, Ullrich; Kösel, Teresa; Herrmann, Jennifer; Krug, Daniel; Boshoff, Helena I. M.; Beckert, Bertrand; Evans, Joanna C.; Schlemmer, Jan; Sloan, Becky; Weiner, Danielle M.; Via, Laura E.; Moosa, Atica; Ioerger, Thomas R.; Graf, Michael; Zinshteyn, Boris; Abdelshahid, Maha; Nguyen, Fabian; Arenz, Stefan; Gille, Franziska; Siebke, Maik; Seedorf, Tim; Plettenburg, Oliver; Green, Rachel; Warnke, Anna-Luisa; Ullrich, Joachim; Warrass, Ralf; Barry, Clifton E.; Warner, Digby F.; Mizrahi, Valerie; Kirschning, Andreas; Wilson, Daniel N.; Müller, Rolf (Washington, DC : ACS Publications, 2023)
    Resistance of bacterial pathogens against antibiotics is declared by WHO as a major global health threat. As novel antibacterial agents are urgently needed, we re-assessed the broad-spectrum myxobacterial antibiotic ...